Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis
Identifieur interne : 000052 ( France/Analysis ); précédent : 000051; suivant : 000053Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis
Auteurs : Marianna Virtanen [Finlande] ; Solja T. Nyberg [Finlande] ; G David Batty [Royaume-Uni] ; Markus Jokela [Finlande] ; Katriina Heikkil [Finlande] ; Eleonor I. Fransson [Suède] ; Lars Alfredsson [Suède] ; Jakob B. Bjorner [Danemark] ; Marianne Borritz [Danemark] ; Hermann Burr [Allemagne] ; Annalisa Casini [Belgique] ; Els Clays [Belgique] ; Dirk De Bacquer [Belgique] ; Nico Dragano [Allemagne] ; Marko Elovainio [Finlande] ; Raimund Erbel [Allemagne] ; Jane E. Ferrie [Royaume-Uni] ; Mark Hamer [Royaume-Uni] ; Karl-Heinz Jöckel [Allemagne] ; France Kittel [Belgique] ; Anders Knutsson [Suède] ; Markku Koskenvuo [Finlande] ; Aki Koskinen [Finlande] ; Thorsten Lunau [Allemagne] ; Ida E H. Madsen [Danemark] ; Martin L. Nielsen [Danemark] ; Maria Nordin [Suède] ; Tuula Oksanen [Finlande] ; Krista Pahkin [Royaume-Uni] ; Jan H. Pejtersen [Danemark] ; Jaana Pentti [Finlande] ; Reiner Rugulies [Danemark] ; Paula Salo [Finlande] ; Martin J. Shipley [Royaume-Uni] ; Johannes Siegrist [Allemagne] ; Andrew Steptoe [Royaume-Uni] ; Sakari B. Suominen [Finlande, Suède] ; Töres Theorell [Suède] ; Salla Toppinen-Tanner [Finlande] ; Ari V N Nen [Finlande] ; Jussi Vahtera [Finlande] ; Peter J M. Westerholm [Suède] ; Hugo Westerlund [Suède] ; Natalie Slopen [États-Unis] ; Ichiro Kawachi [États-Unis] ; Archana Singh-Manoux [Royaume-Uni, France] ; Mika Kivim Ki [Finlande, Royaume-Uni]Source :
- BMJ : British Medical Journal [ 1756-1833 ] ; 2013-08-08.
Abstract
Objective To determine the association between self reported job insecurity and incident coronary heart disease. Design A meta-analysis combining individual level data from a collaborative consortium and published studies identified by a systematic review. Data sources We obtained individual level data from 13 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. Four published prospective cohort studies were identified by searches of Medline (to August 2012) and Embase databases (to October 2012), supplemented by manual searches. Review methods Prospective cohort studies that reported risk estimates for clinically verified incident coronary heart disease by the level of self reported job insecurity. Two independent reviewers extracted published data. Summary estimates of association were obtained using random effects models. Results The literature search yielded four cohort studies. Together with 13 cohort studies with individual participant data, the meta-analysis comprised up to 174 438 participants with a mean follow-up of 9.7 years and 1892 incident cases of coronary heart disease. Age adjusted relative risk of high versus low job insecurity was 1.32 (95% confidence interval 1.09 to 1.59). The relative risk of job insecurity adjusted for sociodemographic and risk factors was 1.19 (1.00 to 1.42). There was no evidence of significant differences in this association by sex, age (<50 v ≥50 years), national unemployment rate, welfare regime, or job insecurity measure. Conclusions The modest association between perceived job insecurity and incident coronary heart disease is partly attributable to poorer socioeconomic circumstances and less favourable risk factor profiles among people with job insecurity.
Url:
DOI: 10.1136/bmj.f4746
Affiliations:
- Allemagne, Belgique, Danemark, Finlande, France, Royaume-Uni, Suède, États-Unis
- Angleterre, Berlin, East Middle Sweden, Finlande occidentale, Grand Londres, Hovedstaden, Massachusetts, Région de Bruxelles-Capitale, Svealand, Uusimaa, Écosse
- Berlin, Bruxelles, Cambridge (Massachusetts), Copenhague, Helsinki, Londres, Stockholm, Turku, Uppsala, Édimbourg
- University College de Londres, Université Harvard, Université d'Helsinki, Université d'Uppsala, Université d'Édimbourg, Université de Stockholm, Université de Turku, Université libre de Bruxelles
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Bjorner</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>National Research Centre for the Working Environment, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Borritz, Marianne" sort="Borritz, Marianne" uniqKey="Borritz M" first="Marianne" last="Borritz">Marianne Borritz</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Burr, Hermann" sort="Burr, Hermann" uniqKey="Burr H" first="Hermann" last="Burr">Hermann Burr</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Federal Institute for Occupational Safety and Health (BAuA), Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Casini, Annalisa" sort="Casini, Annalisa" uniqKey="Casini A" first="Annalisa" last="Casini">Annalisa Casini</name><affiliation wicri:level="4"><country xml:lang="fr">Belgique</country><wicri:regionArea>School of Public Health, Université Libre de Bruxelles, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Clays, Els" sort="Clays, Els" uniqKey="Clays E" first="Els" last="Clays">Els Clays</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Public Health, Ghent University, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="De Bacquer, Dirk" sort="De Bacquer, Dirk" uniqKey="De Bacquer D" first="Dirk" last="De Bacquer">Dirk De Bacquer</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Public Health, Ghent University, Ghent</wicri:regionArea><wicri:noRegion>Ghent</wicri:noRegion></affiliation></author><author><name sortKey="Dragano, Nico" sort="Dragano, Nico" uniqKey="Dragano N" first="Nico" last="Dragano">Nico Dragano</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf</wicri:regionArea><wicri:noRegion>Düsseldorf</wicri:noRegion><wicri:noRegion>Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Elovainio, Marko" sort="Elovainio, Marko" uniqKey="Elovainio M" first="Marko" last="Elovainio">Marko Elovainio</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Cardiology, West-German Heart Center Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Ferrie, Jane E" sort="Ferrie, Jane E" uniqKey="Ferrie J" first="Jane E" last="Ferrie">Jane E. Ferrie</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Community and Social Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Hamer, Mark" sort="Hamer, Mark" uniqKey="Hamer M" first="Mark" last="Hamer">Mark Hamer</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry, and Epidemiology, University Duisburg-Essen</wicri:regionArea><wicri:noRegion>University Duisburg-Essen</wicri:noRegion><wicri:noRegion>University Duisburg-Essen</wicri:noRegion></affiliation></author><author><name sortKey="Kittel, France" sort="Kittel, France" uniqKey="Kittel F" first="France" last="Kittel">France Kittel</name><affiliation wicri:level="4"><country xml:lang="fr">Belgique</country><wicri:regionArea>School of Public Health, Université Libre de Bruxelles, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Knutsson, Anders" sort="Knutsson, Anders" uniqKey="Knutsson A" first="Anders" last="Knutsson">Anders Knutsson</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Health Sciences, Mid Sweden University, Sundsvall</wicri:regionArea><wicri:noRegion>Sundsvall</wicri:noRegion></affiliation></author><author><name sortKey="Koskenvuo, Markku" sort="Koskenvuo, Markku" uniqKey="Koskenvuo M" first="Markku" last="Koskenvuo">Markku Koskenvuo</name><affiliation wicri:level="4"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Helsinki</wicri:regionArea><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName><orgName type="university">Université d'Helsinki</orgName></affiliation></author><author><name sortKey="Koskinen, Aki" sort="Koskinen, Aki" uniqKey="Koskinen A" first="Aki" last="Koskinen">Aki Koskinen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Lunau, Thorsten" sort="Lunau, Thorsten" uniqKey="Lunau T" first="Thorsten" last="Lunau">Thorsten Lunau</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf</wicri:regionArea><wicri:noRegion>Düsseldorf</wicri:noRegion><wicri:noRegion>Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Madsen, Ida E H" sort="Madsen, Ida E H" uniqKey="Madsen I" first="Ida E H" last="Madsen">Ida E H. Madsen</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>National Research Centre for the Working Environment, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Nielsen, Martin L" sort="Nielsen, Martin L" uniqKey="Nielsen M" first="Martin L" last="Nielsen">Martin L. Nielsen</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Nordin, Maria" sort="Nordin, Maria" uniqKey="Nordin M" first="Maria" last="Nordin">Maria Nordin</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Psychology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Oksanen, Tuula" sort="Oksanen, Tuula" uniqKey="Oksanen T" first="Tuula" last="Oksanen">Tuula Oksanen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Pahkin, Krista" sort="Pahkin, Krista" uniqKey="Pahkin K" first="Krista" last="Pahkin">Krista Pahkin</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Pejtersen, Jan H" sort="Pejtersen, Jan H" uniqKey="Pejtersen J" first="Jan H" last="Pejtersen">Jan H. Pejtersen</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish National Centre for Social Research, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Pentti, Jaana" sort="Pentti, Jaana" uniqKey="Pentti J" first="Jaana" last="Pentti">Jaana Pentti</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Rugulies, Reiner" sort="Rugulies, Reiner" uniqKey="Rugulies R" first="Reiner" last="Rugulies">Reiner Rugulies</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>National Research Centre for the Working Environment, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Public Health and Department of Psychology, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Salo, Paula" sort="Salo, Paula" uniqKey="Salo P" first="Paula" last="Salo">Paula Salo</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Psychology, University of Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName><orgName type="university">Université de Turku</orgName></affiliation></author><author><name sortKey="Shipley, Martin J" sort="Shipley, Martin J" uniqKey="Shipley M" first="Martin J" last="Shipley">Martin J. Shipley</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Siegrist, Johannes" sort="Siegrist, Johannes" uniqKey="Siegrist J" first="Johannes" last="Siegrist">Johannes Siegrist</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf</wicri:regionArea><wicri:noRegion>Düsseldorf</wicri:noRegion><wicri:noRegion>Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Steptoe, Andrew" sort="Steptoe, Andrew" uniqKey="Steptoe A" first="Andrew" last="Steptoe">Andrew Steptoe</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Suominen, Sakari B" sort="Suominen, Sakari B" uniqKey="Suominen S" first="Sakari B" last="Suominen">Sakari B. Suominen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName><orgName type="university">Université de Turku</orgName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Nordic School of Public Health, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Theorell, Tores" sort="Theorell, Tores" uniqKey="Theorell T" first="Töres" last="Theorell">Töres Theorell</name><affiliation wicri:level="4"><country xml:lang="fr">Suède</country><wicri:regionArea>Stress Research Institute, Stockholm University, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName><orgName type="university">Université de Stockholm</orgName></affiliation></author><author><name sortKey="Toppinen Tanner, Salla" sort="Toppinen Tanner, Salla" uniqKey="Toppinen Tanner S" first="Salla" last="Toppinen-Tanner">Salla Toppinen-Tanner</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="V N Nen, Ari" sort="V N Nen, Ari" uniqKey="V N Nen A" first="Ari" last="V N Nen">Ari V N Nen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Vahtera, Jussi" sort="Vahtera, Jussi" uniqKey="Vahtera J" first="Jussi" last="Vahtera">Jussi Vahtera</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Public Health, University of Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName><orgName type="university">Université de Turku</orgName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Finlande</country><wicri:regionArea>Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Westerholm, Peter J M" sort="Westerholm, Peter J M" uniqKey="Westerholm P" first="Peter J M" last="Westerholm">Peter J M. Westerholm</name><affiliation wicri:level="4"><country xml:lang="fr">Suède</country><wicri:regionArea>Occupational and Environmental Medicine, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Westerlund, Hugo" sort="Westerlund, Hugo" uniqKey="Westerlund H" first="Hugo" last="Westerlund">Hugo Westerlund</name><affiliation wicri:level="4"><country xml:lang="fr">Suède</country><wicri:regionArea>Stress Research Institute, Stockholm University, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName><orgName type="university">Université de Stockholm</orgName></affiliation></author><author><name sortKey="Slopen, Natalie" sort="Slopen, Natalie" uniqKey="Slopen N" first="Natalie" last="Slopen">Natalie Slopen</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for the Developing Child, Harvard University, Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Kawachi, Ichiro" sort="Kawachi, Ichiro" uniqKey="Kawachi I" first="Ichiro" last="Kawachi">Ichiro Kawachi</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Society, Human Development and Health, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Singh Manoux, Archana" sort="Singh Manoux, Archana" uniqKey="Singh Manoux A" first="Archana" last="Singh-Manoux">Archana Singh-Manoux</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Inserm U1018, Centre for Research in Epidemiology and Population Health, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Kivim Ki, Mika" sort="Kivim Ki, Mika" uniqKey="Kivim Ki M" first="Mika" last="Kivim Ki">Mika Kivim Ki</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, FI-00250 Helsinki</wicri:regionArea><wicri:noRegion>FI-00250 Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Public Health, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Behavioral Sciences, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">BMJ : British Medical Journal</title><title level="j" type="abbrev">BMJ</title><idno type="eISSN">1756-1833</idno><imprint><publisher>British Medical Journal Publishing Group</publisher><date type="published" when="2013-08-08">2013-08-08</date><biblScope unit="volume">347</biblScope></imprint></series><idno type="istex">AD8D78CF99EEC7148C1B93D6F27DED0B2ECC73C0</idno><idno type="DOI">10.1136/bmj.f4746</idno><idno type="href">bmj-347-bmj-f4746.pdf</idno><idno type="ArticleID">virm012156</idno><idno type="local">bmj;347/aug08_1/f4746</idno></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objective To determine the association between self reported job insecurity and incident coronary heart disease. Design A meta-analysis combining individual level data from a collaborative consortium and published studies identified by a systematic review. Data sources We obtained individual level data from 13 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. Four published prospective cohort studies were identified by searches of Medline (to August 2012) and Embase databases (to October 2012), supplemented by manual searches. Review methods Prospective cohort studies that reported risk estimates for clinically verified incident coronary heart disease by the level of self reported job insecurity. Two independent reviewers extracted published data. Summary estimates of association were obtained using random effects models. Results The literature search yielded four cohort studies. Together with 13 cohort studies with individual participant data, the meta-analysis comprised up to 174 438 participants with a mean follow-up of 9.7 years and 1892 incident cases of coronary heart disease. Age adjusted relative risk of high versus low job insecurity was 1.32 (95% confidence interval 1.09 to 1.59). The relative risk of job insecurity adjusted for sociodemographic and risk factors was 1.19 (1.00 to 1.42). There was no evidence of significant differences in this association by sex, age (<50 v ≥50 years), national unemployment rate, welfare regime, or job insecurity measure. Conclusions The modest association between perceived job insecurity and incident coronary heart disease is partly attributable to poorer socioeconomic circumstances and less favourable risk factor profiles among people with job insecurity.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Belgique</li><li>Danemark</li><li>Finlande</li><li>France</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Berlin</li><li>East Middle Sweden</li><li>Finlande occidentale</li><li>Grand Londres</li><li>Hovedstaden</li><li>Massachusetts</li><li>Région de Bruxelles-Capitale</li><li>Svealand</li><li>Uusimaa</li><li>Écosse</li></region><settlement><li>Berlin</li><li>Bruxelles</li><li>Cambridge (Massachusetts)</li><li>Copenhague</li><li>Helsinki</li><li>Londres</li><li>Stockholm</li><li>Turku</li><li>Uppsala</li><li>Édimbourg</li></settlement><orgName><li>University College de Londres</li><li>Université Harvard</li><li>Université d'Helsinki</li><li>Université d'Uppsala</li><li>Université d'Édimbourg</li><li>Université de Stockholm</li><li>Université de Turku</li><li>Université libre de Bruxelles</li></orgName></list><tree><country name="Finlande"><noRegion><name sortKey="Virtanen, Marianna" sort="Virtanen, Marianna" uniqKey="Virtanen M" first="Marianna" last="Virtanen">Marianna Virtanen</name></noRegion><name sortKey="Elovainio, Marko" sort="Elovainio, Marko" uniqKey="Elovainio M" first="Marko" last="Elovainio">Marko Elovainio</name><name sortKey="Heikkil, Katriina" sort="Heikkil, Katriina" uniqKey="Heikkil K" first="Katriina" last="Heikkil">Katriina Heikkil</name><name sortKey="Jokela, Markus" sort="Jokela, Markus" uniqKey="Jokela M" first="Markus" last="Jokela">Markus Jokela</name><name sortKey="Kivim Ki, Mika" sort="Kivim Ki, Mika" uniqKey="Kivim Ki M" first="Mika" last="Kivim Ki">Mika Kivim Ki</name><name sortKey="Kivim Ki, Mika" sort="Kivim Ki, Mika" uniqKey="Kivim Ki M" first="Mika" last="Kivim Ki">Mika Kivim Ki</name><name sortKey="Koskenvuo, Markku" sort="Koskenvuo, Markku" uniqKey="Koskenvuo M" first="Markku" last="Koskenvuo">Markku Koskenvuo</name><name sortKey="Koskinen, Aki" sort="Koskinen, Aki" uniqKey="Koskinen A" first="Aki" last="Koskinen">Aki Koskinen</name><name sortKey="Nyberg, Solja T" sort="Nyberg, Solja T" uniqKey="Nyberg S" first="Solja T" last="Nyberg">Solja T. Nyberg</name><name sortKey="Oksanen, Tuula" sort="Oksanen, Tuula" uniqKey="Oksanen T" first="Tuula" last="Oksanen">Tuula Oksanen</name><name sortKey="Pentti, Jaana" sort="Pentti, Jaana" uniqKey="Pentti J" first="Jaana" last="Pentti">Jaana Pentti</name><name sortKey="Salo, Paula" sort="Salo, Paula" uniqKey="Salo P" first="Paula" last="Salo">Paula Salo</name><name sortKey="Salo, Paula" sort="Salo, Paula" uniqKey="Salo P" first="Paula" last="Salo">Paula Salo</name><name sortKey="Suominen, Sakari B" sort="Suominen, Sakari B" uniqKey="Suominen S" first="Sakari B" last="Suominen">Sakari B. Suominen</name><name sortKey="Suominen, Sakari B" sort="Suominen, Sakari B" uniqKey="Suominen S" first="Sakari B" last="Suominen">Sakari B. Suominen</name><name sortKey="Toppinen Tanner, Salla" sort="Toppinen Tanner, Salla" uniqKey="Toppinen Tanner S" first="Salla" last="Toppinen-Tanner">Salla Toppinen-Tanner</name><name sortKey="V N Nen, Ari" sort="V N Nen, Ari" uniqKey="V N Nen A" first="Ari" last="V N Nen">Ari V N Nen</name><name sortKey="Vahtera, Jussi" sort="Vahtera, Jussi" uniqKey="Vahtera J" first="Jussi" last="Vahtera">Jussi Vahtera</name><name sortKey="Vahtera, Jussi" sort="Vahtera, Jussi" uniqKey="Vahtera J" first="Jussi" last="Vahtera">Jussi Vahtera</name><name sortKey="Vahtera, Jussi" sort="Vahtera, Jussi" uniqKey="Vahtera J" first="Jussi" last="Vahtera">Jussi Vahtera</name><name sortKey="Virtanen, Marianna" sort="Virtanen, Marianna" uniqKey="Virtanen M" first="Marianna" last="Virtanen">Marianna Virtanen</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Batty, G David" sort="Batty, G David" uniqKey="Batty G" first="G David" last="Batty">G David Batty</name></region><name sortKey="Batty, G David" sort="Batty, G David" uniqKey="Batty G" first="G David" last="Batty">G David Batty</name><name sortKey="Ferrie, Jane E" sort="Ferrie, Jane E" uniqKey="Ferrie J" first="Jane E" last="Ferrie">Jane E. Ferrie</name><name sortKey="Ferrie, Jane E" sort="Ferrie, Jane E" uniqKey="Ferrie J" first="Jane E" last="Ferrie">Jane E. Ferrie</name><name sortKey="Hamer, Mark" sort="Hamer, Mark" uniqKey="Hamer M" first="Mark" last="Hamer">Mark Hamer</name><name sortKey="Kivim Ki, Mika" sort="Kivim Ki, Mika" uniqKey="Kivim Ki M" first="Mika" last="Kivim Ki">Mika Kivim Ki</name><name sortKey="Pahkin, Krista" sort="Pahkin, Krista" uniqKey="Pahkin K" first="Krista" last="Pahkin">Krista Pahkin</name><name sortKey="Shipley, Martin J" sort="Shipley, Martin J" uniqKey="Shipley M" first="Martin J" last="Shipley">Martin J. Shipley</name><name sortKey="Singh Manoux, Archana" sort="Singh Manoux, Archana" uniqKey="Singh Manoux A" first="Archana" last="Singh-Manoux">Archana Singh-Manoux</name><name sortKey="Steptoe, Andrew" sort="Steptoe, Andrew" uniqKey="Steptoe A" first="Andrew" last="Steptoe">Andrew Steptoe</name></country><country name="Suède"><noRegion><name sortKey="Fransson, Eleonor I" sort="Fransson, Eleonor I" uniqKey="Fransson E" first="Eleonor I" last="Fransson">Eleonor I. Fransson</name></noRegion><name sortKey="Alfredsson, Lars" sort="Alfredsson, Lars" uniqKey="Alfredsson L" first="Lars" last="Alfredsson">Lars Alfredsson</name><name sortKey="Alfredsson, Lars" sort="Alfredsson, Lars" uniqKey="Alfredsson L" first="Lars" last="Alfredsson">Lars Alfredsson</name><name sortKey="Fransson, Eleonor I" sort="Fransson, Eleonor I" uniqKey="Fransson E" first="Eleonor I" last="Fransson">Eleonor I. Fransson</name><name sortKey="Fransson, Eleonor I" sort="Fransson, Eleonor I" uniqKey="Fransson E" first="Eleonor I" last="Fransson">Eleonor I. Fransson</name><name sortKey="Knutsson, Anders" sort="Knutsson, Anders" uniqKey="Knutsson A" first="Anders" last="Knutsson">Anders Knutsson</name><name sortKey="Nordin, Maria" sort="Nordin, Maria" uniqKey="Nordin M" first="Maria" last="Nordin">Maria Nordin</name><name sortKey="Suominen, Sakari B" sort="Suominen, Sakari B" uniqKey="Suominen S" first="Sakari B" last="Suominen">Sakari B. Suominen</name><name sortKey="Theorell, Tores" sort="Theorell, Tores" uniqKey="Theorell T" first="Töres" last="Theorell">Töres Theorell</name><name sortKey="Westerholm, Peter J M" sort="Westerholm, Peter J M" uniqKey="Westerholm P" first="Peter J M" last="Westerholm">Peter J M. 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Pejtersen</name><name sortKey="Rugulies, Reiner" sort="Rugulies, Reiner" uniqKey="Rugulies R" first="Reiner" last="Rugulies">Reiner Rugulies</name><name sortKey="Rugulies, Reiner" sort="Rugulies, Reiner" uniqKey="Rugulies R" first="Reiner" last="Rugulies">Reiner Rugulies</name></country><country name="Allemagne"><region name="Berlin"><name sortKey="Burr, Hermann" sort="Burr, Hermann" uniqKey="Burr H" first="Hermann" last="Burr">Hermann Burr</name></region><name sortKey="Dragano, Nico" sort="Dragano, Nico" uniqKey="Dragano N" first="Nico" last="Dragano">Nico Dragano</name><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><name sortKey="Lunau, Thorsten" sort="Lunau, Thorsten" uniqKey="Lunau T" first="Thorsten" last="Lunau">Thorsten Lunau</name><name sortKey="Siegrist, Johannes" sort="Siegrist, Johannes" uniqKey="Siegrist J" first="Johannes" last="Siegrist">Johannes Siegrist</name></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Casini, Annalisa" sort="Casini, Annalisa" uniqKey="Casini A" first="Annalisa" last="Casini">Annalisa Casini</name></region><name sortKey="Clays, Els" sort="Clays, Els" uniqKey="Clays E" first="Els" last="Clays">Els Clays</name><name sortKey="De Bacquer, Dirk" sort="De Bacquer, Dirk" uniqKey="De Bacquer D" first="Dirk" last="De Bacquer">Dirk De Bacquer</name><name sortKey="Kittel, France" sort="Kittel, France" uniqKey="Kittel F" first="France" last="Kittel">France Kittel</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Slopen, Natalie" sort="Slopen, Natalie" uniqKey="Slopen N" first="Natalie" last="Slopen">Natalie Slopen</name></region><name sortKey="Kawachi, Ichiro" sort="Kawachi, Ichiro" uniqKey="Kawachi I" first="Ichiro" last="Kawachi">Ichiro Kawachi</name><name sortKey="Slopen, Natalie" sort="Slopen, Natalie" uniqKey="Slopen N" first="Natalie" last="Slopen">Natalie Slopen</name></country><country name="France"><noRegion><name sortKey="Singh Manoux, Archana" sort="Singh Manoux, Archana" uniqKey="Singh Manoux A" first="Archana" last="Singh-Manoux">Archana Singh-Manoux</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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